N-Boc-piperazine

N-Boc-piperazine is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183) [1].

Product Specifications

CAS Number

[57260-71-6]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-boc-piperazine.html

Purity

99.99

Solubility

10 mM in DMSO

Smiles

O=C(OC(C)(C)C)N1CCNCC1

Molecular Formula

C9H18N2O2

Molecular Weight

186.25

Precautions

H315, H319, H335

References & Citations

[1]Binbin Cheng, et al. Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1. Eur J Med Chem. 2020;199:112377.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers

Available Sizes

Curated Selection

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