N-Boc-piperazine
Product Specifications
UNSPSC Description
N-Boc-piperazine is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183)[1].
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-boc-piperazine.html
Purity
99.97
Solubility
10 mM in DMSO
Smiles
O=C(OC(C)(C)C)N1CCNCC1
Molecular Weight
186.25
References & Citations
[1]Binbin Cheng, et al. Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1. Eur J Med Chem. 2020;199:112377.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-30105/N-Boc-piperazine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-30105/N-Boc-piperazine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
57260-71-6
Available Sizes
Curated Selection
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