Ac-[Nle4, D-Phe7]-α-MSH (4-10) -NH2
Ac-[Nle4, D-Phe7]-α-MSH (4-10) -NH2 is a melanotropin, a melanocyte-stimulating hormone. Ac-[Nle4, D-Phe7]-α-MSH (4-10) -NH2 stimulates tyrosinase and exhibits thermoregulatory effect in rats model[1][2].
Product Specifications
CAS Number
82188-67-8
UNSPSC
12352209
Target
Tyrosinase
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ac-nle4-d-phe7-α-msh-4-10-nh2.html
Purity
99.50
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CCCC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC1=CNC=N1)C(N[C@H](CC2=CC=CC=C2)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(NCC(N)=O)=O)=O)=O)=O)=O)=O)C
Molecular Formula
C47H64N14O10
Molecular Weight
985.10
References & Citations
[1]Marwan MM, et al. Stimulation of S91 melanoma tyrosinase activity by superpotent alpha-melanotropins. Mol Cell Endocrinol. 1985 Jul;41 (2-3) :171-7. |[2]Lyn H, et al. α-Melanocyte-stimulating hormone (MSH) and [Nle4, D-Phe7]-α-MSH: Effects on core temperature in rats. Pharmacology Biochemistry and Behavior. 1993;44 (3) :533-538.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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