TC13172-NH-COOH

TC13172-NH-COOH is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs) . TC13172-NH-COOH can be used for synthesis PROTAC MLKL Degrader-2 (HY-169072) [1].

Product Specifications

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/tc13172-nh-cooh.html

Smiles

O=C(O)NC1=CC=CC(C#CCN(C(N(C2=O)C)=O)C3=C2N(C(S(C)(=O)=O)=N3)C)=C1

Molecular Formula

C18H17N5O6S

Molecular Weight

431.42

References & Citations

[1]Li S, et al. Discovery of Covalent MLKL PROTAC Degraders via Optimization of a Theophylline Derivative Ligand for Treating Necroptosis. J Med Chem. 2024 Sep 12;67 (17) :15353-15372.