BTX-A51
BTX-A51 (Casein Kinase inhibitor A51) is a potent and orally active casein kinase 1α (CK1α) inhibitor. BTX-A51 induces leukemia cell apoptosis, and has potent anti-leukemic activities[1].
Product Specifications
CAS Number
[2079068-74-7]
Product Name Alternative
Casein Kinase inhibitor A51
UNSPSC
12352005
Target
Apoptosis; Casein Kinase; CDK
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/btx-a51.html
Concentration
10mM
Purity
98.58
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N[C@H]1CC[C@H](NC2=NC=C(Cl)C(C3=C(CC4CC4)N(C)N=C3)=N2)CC1
Molecular Formula
C18H25ClN6
Molecular Weight
360.88
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-123954/BTX-A51-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-123954/BTX-A51-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
CDK7; CDK9; CK1
Available Sizes
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