RSK Substrate

<strong>RSK Substrate</strong>_x000D_ <strong>Catalog number:</strong> B2013652_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong>_x000D_ 1242.5_x000D_ <strong>Supplied as:</strong> Lyophilized powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> RSK Substrate_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Roskoski R Jr. Targeting ERK1/2 protein-serine/threonine kinases in human cancers Pharmacol Res. 2019 Apr;142:151-168._x000D_ 2: Mayor-Ruiz C, Bauer S, Brand M, Kozicka Z, Siklos M, Imrichova H, Kaltheuner IH, Hahn E, Seiler K, Koren A, Petzold G, Fellner M, Bock C, M_ller AC, Zuber J, Geyer M, Thom_ NH, Kubicek S, Winter GE. Rational discovery of molecular glue degraders via scalable chemical profiling Nat Chem Biol. 2020 Nov;16(11):1199-1207._x000D_ 3: Cargnello M, Roux PP. Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases Microbiol Mol Biol Rev. 2011 Mar;75(1):50-83._x000D_ 4: Houles T, Roux PP. Defining the role of the RSK isoforms in cancer Semin Cancer Biol. 2018 Feb;48:53-61._x000D_ 5: Motta M, Pannone L, Pantaleoni F, Bocchinfuso G, Radio FC, Cecchetti S, Ciolfi A, Di Rocco M, Elting MW, Brilstra EH, Boni S, Mazzanti L, Tamburrino F, Walsh L, Payne K, Fernndez-Jan A, Ganapathi M, Chung WK, Grange DK, Dave-Wala A, Reshmi SC, Bartholomew DW, Mouhlas D, Carpentieri G, Bruselles A, Pizzi S, Bellacchio E, Piceci-Sparascio F, Liewski C, Brinkmann J, Waclaw RR, Waisfisz Q, van Gassen K, Wentzensen IM, Morrow MM, lvarez S, Mart_nez-Garc_a M, De Luca A, Memo L, Zampino G, Rossi C, Seri M, Gelb BD, Zenker M, Dallapiccola B, Stella L, Prada CE, Martinelli S, Flex E, Tartaglia M. Enhanced MAPK1 Function Causes a Neurodevelopmental Disorder within the RASopathy Clinical Spectrum Am J Hum Genet. 2020 Sep 3;107(3):499-513._x000D_ 6: Casalvieri KA, Matheson CJ, Backos DS, Reigan P. Selective Targeting of RSK Isoforms in Cancer Trends Cancer. 2017 Apr;3(4):302-312._x000D_ 7: Romeo Y, Zhang X, Roux PP. Regulation and function of the RSK family of protein kinases Biochem J. 2012 Jan 15;441(2):553-69._x000D_ 8: Alexa A, Sok P, Gross F, Albert K, Kobori E, P_ti L, G_gl G, Bento I, Kuang E, Taylor SS, Zhu F, Ciliberto A, Remnyi A. A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host Nat Commun. 2022 Jan 25;13(1):472._x000D_ 9: Carriere A, Ray H, Blenis J, Roux PP. The RSK factors of activating the Ras/MAPK signaling cascade Front Biosci. 2008 May 1;13:4258-75._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/18813292">10: Anjum R, Blenis J. The RSK family of kinases: emerging roles in cellular signalling Nat Rev Mol Cell Biol. 2008 Oct;9(10):747-58. </a>_x000D_ _x000D_ <strong>Products Related to RSK Substrate can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>