Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

BAY-320

BAY-320 is a selective and ATP-competitive Bub1 inhibitor that inhibits the kinase activity of Bub1 with an IC50 of 680 nM. BAY-320 inhibits endogenous Bub1-mediated Sgo1 localization. BAY-320 affects cellular mitotic chromosome arrangement and spindle assembly. BAY-320 inhibits cell proliferation. BAY-320 can be used in the study of cancer such as ovarian cancer and cervical cancer[1][2].

Product Specifications

CAS Number

1445830-50-1

UNSPSC

12352005

Target

Ser/Thr Kinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/BAY-320.html

Purity

99.74

Solubility

DMSO : 83.33 mg/mL (ultrasonic)

Smiles

COC1=CN=C(C2=NN(CC3=C(F)C=C(OCC)C=C3F)C(C4CC4)=C2C)N=C1NC5=CC=NC=C5

Molecular Formula

C26H26F2N6O2

Molecular Weight

492.52

References & Citations

[1]Baron AP, et al. Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524. Elife. 2016 Feb 17;5. pii: e12187.|[2]Amalina I, et al. Inhibitors of the Bub1 spindle assembly checkpoint kinase: synthesis of BAY-320 and comparison with 2OH-BNPP1. R Soc Open Sci. 2021 Dec 15;8 (12) :210854.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Frozen Tissue Blocks, Lung: right upper lobe
CB504616 1 Block

Frozen Tissue Blocks, Lung: right upper lobe

Sign In for Pricing
View Details
CCN2 Mouse Monoclonal Antibody [Clone ID: OTI5C10]
CF806800 100 µg

CCN2 Mouse Monoclonal Antibody [Clone ID: OTI5C10]

Sign In for Pricing
View Details
SLC39A5 (NM_173596) Human Recombinant Protein
TP306665 20 µg

SLC39A5 (NM_173596) Human Recombinant Protein

Sign In for Pricing
View Details
GSTA1 Polyclonal Antibody
D-AB-10164L-01 25 µL

GSTA1 Polyclonal Antibody

Sign In for Pricing
View Details
GSTA1 Polyclonal Antibody
D-AB-10164L-02 100 µL

GSTA1 Polyclonal Antibody

Sign In for Pricing
View Details
Doxylamine N, N’-Dioxide
TRC-D562025-50MG 50 mg

Doxylamine N, N’-Dioxide

Sign In for Pricing
View Details