ACSS2-IN-2
ACSS2-IN-2 is an acyl-CoA synthetase short-chain family member 2 (ACSS2) inhibitor. ACSS2-IN-2 can inhibit ACSS2 activity with an IC50 value of 3.8 nM. ACSS2-IN-2 can be used for the research of several diseases, such as viral infection, metabolic disorders, neuropsychiatric diseases, inflammatory/autoimmune conditions and cancer[1].
Product Specifications
CAS Number
[2332820-04-7]
UNSPSC
12352005
Target
Acetyl-CoA synthetase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/acss2-in-2.html
Purity
99.49
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(OC)C1=CC=CC(N2N=C(C)C(C(NC3=CC=CC(C(F)(F)C)=C3)=O)C2=O)=C1
Molecular Formula
C21H19F2N3O4
Molecular Weight
415.39
References & Citations
[1]Philippe Nakache, et al. Acss2 inhibitors and methods of use thereof. Patent. WO2019097515A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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