Alcaftadine carboxylic acid
Alcaftadine carboxylic acid is a broad-spectrum antihistamine compound with high affinity for histamine H1 and H2 receptors and low affinity for H4 receptors. Alcaftadine carboxylic acid has also demonstrated effects on modulating immune cell recruitment and stabilizing mast cells. Alcaftadine carboxylic acid is more effective than placebo in preventing ocular itching associated with allergic conjunctivitis and is at least as effective as olopatadine 0.01%[1].
Product Specifications
CAS Number
[147083-93-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alcaftadine-carboxylic-acid.html
Smiles
O=C(O)C1=CN=C2N1CCC3=CC=CC=C3/C2=C4CCN(CC/4)C
Molecular Formula
C19H21N3O2
Molecular Weight
323.39
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Alcaftadine: a topical antihistamine for use in allergic conjunctivitis
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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