Alcaftadine carboxylic acid
Product Specifications
UNSPSC Description
Alcaftadine carboxylic acid is a broad-spectrum antihistamine compound with high affinity for histamine H1 and H2 receptors and low affinity for H4 receptors. Alcaftadine carboxylic acid has also demonstrated effects on modulating immune cell recruitment and stabilizing mast cells. Alcaftadine carboxylic acid is more effective than placebo in preventing ocular itching associated with allergic conjunctivitis and is at least as effective as olopatadine 0.01%[1].
Target Antigen
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alcaftadine-carboxylic-acid.html
Smiles
O=C(O)C1=CN=C2N1CCC3=CC=CC=C3/C2=C4CCN(CC/4)C
Molecular Weight
323.39
References & Citations
[1]Alcaftadine: a topical antihistamine for use in allergic conjunctivitis
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-124356/Alcaftadine-carboxylic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-124356/
Clinical Information
No Development Reported
CAS Number
147083-93-0
Curated Selection
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