Anti-Hu CD226 Purified
CD226 is a type I transmembrane glycoprotein, which is expressed after activation on NK cells, platelets, monocytes, and some T cells. Its expression is increased in patients suffering from some autoimmune diseases or viral infections. CD226 is being phosphorylated on its cytoplasmic tail and interacts with LFA-1 complex (CD11a/CD18), resulting in calcium-independent intercellular contacts. Ligands for CD226 are CD155 and CD112.
Product Specifications
Certification
RUO
Target Antigen
CD226
Clone
11A8
Applications
FC (QC tested)
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
The mouse monoclonal antibody 11A8 recognizes an extracellular epitope within CD226 transmembrane glycoprotein.
Species
Non-human primates, Human
CAS Number
9007-83-4
Isotype
Mouse IgG1 kappa
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