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StA-IFN-1

StA-IFN-1 is an inhibitor for type I interferon (IFN), that inhibits the activation of IFNβ with an IC50 of 4.1 μM[1].

Product Specifications

CAS Number

[300839-31-0]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

IFNAR

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sta-ifn-1.html

Smiles

O=C1NN=C(C)C1C2=CN(C(C)=O)C3=C2C=CC=C3

Molecular Formula

C14H13N3O2

Molecular Weight

255.27

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Gage ZO, et al., Identification of Novel Inhibitors of the Type I Interferon Induction Pathway Using Cell-Based High-Throughput Screening. J Biomol Screen. 2016 Oct;21 (9) :978-88.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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