Psoralenoside

Psoralenoside is a benzofuran glycoside from Psoralea corylifolia[1]. Psoralenoside exhibits high binding affinities against histaminergic H1, calmodulin, and voltage-gated L-type calcium channels (E-value≥-6.5 Kcal/mol) [2]. Psoralenoside shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity[3].

Product Specifications

CAS Number

[905954-17-8]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Calcium Channel; Calmodulin; Histamine Receptor

Type

Natural Products

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/psoralenoside.html

Purity

99.84

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)/C=C\C1=C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)C=C(OC=C3)C3=C1

Molecular Formula

C17H18O9

Molecular Weight

366.32

Precautions

H315, H319

References & Citations

[1]Chun-Feng Qiao, et al.Psoralenoside and isopsoralenoside, two new benzofuran glycosides from Psoralea corylifolia. Chem Pharm Bull (Tokyo) . 2006 May;54 (5) :714-6.|[2]Muhammad Bilal Riaz, et al. Pharmacological and computational evaluation of fig for therapeutic potential in hyperactive gastrointestinal disorders. BMC Complement Altern Med. 2019 Dec 3;19 (1) :348.|[3]Yue-Fei Wang, et al.A UPLC-MS/MS method for in vivo and in vitro pharmacokinetic studies of psoralenoside, isopsoralenoside, psoralen and isopsoralen from Psoralea corylifolia extract. J Ethnopharmacol