4′-Hydroxyflavone

4′-Hydroxyflavone (compound 50) can inhibit aldose reductase, with IC50 12 μM[1].

Product Specifications

CAS Number

[4143-63-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Aldose Reductase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Assay Protocol

https://www.medchemexpress.com/4-hydroxyflavone.html

Purity

97.0

Smiles

C1=CC=C2C(=C1)C(=O)C=C(C3=CC=C(C=C3)O)O2

Molecular Formula

C15H10O3

Molecular Weight

238.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Michael Fernández, et al. Quantitative structure-activity relationship to predict differential inhibition of aldose reductase by flavonoid compounds. Bioorg Med Chem. 2005 May 2;13 (9) :3269-77.

Shipping Conditions

Room Temperature

Storage Conditions

RT, protect from light, stored under nitrogen

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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