4′-Hydroxyflavone
4′-Hydroxyflavone (compound 50) can inhibit aldose reductase, with IC50 12 μM[1].
Product Specifications
CAS Number
[4143-63-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Assay Protocol
https://www.medchemexpress.com/4-hydroxyflavone.html
Purity
97.0
Smiles
C1=CC=C2C(=C1)C(=O)C=C(C3=CC=C(C=C3)O)O2
Molecular Formula
C15H10O3
Molecular Weight
238.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Michael Fernández, et al. Quantitative structure-activity relationship to predict differential inhibition of aldose reductase by flavonoid compounds. Bioorg Med Chem. 2005 May 2;13 (9) :3269-77.
Shipping Conditions
Room Temperature
Storage Conditions
RT, protect from light, stored under nitrogen
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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