Adrenocorticotropic Hormone (ACTH) (1-39), human

Adrenocorticotropic Hormone (ACTH) (1-39), human is a melanocortin receptor agonist.

Product Specifications

CAS Number

[12279-41-3]

Product Name Alternative

1-39-Corticotropin (human)

UNSPSC

12352209

Hazard Statement

H302+H312+H332, H351

Target

Melanocortin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Adrenocorticotropic_Hormone__ACTH___1-39_,_human.html

Purity

99.94

Solubility

H2O : ≥ 100 mg/mL

Smiles

O=C([C@@H](N)CO)N[C@H](C(N[C@H](C(N[C@HO=C([C@@H](N)CO)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N1[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N3[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC5=CC=CC=C5)=O)CCC(O)=O)=O)CC(C)C)=O)CCC4)=O)CC6=CC=CC=C6)=O)C)=O)CCC(O)=O)=O)C)=O)CO)=O)CCC(O)=O)=O)CC(O)=O)=O)CCC(O)=O)=O)C)=O)=O)CC(N)=O)=O)CCC3)=O)CC7=CC=C(O)C=C7)=O)C(C)C)=O)CCCCN)=O)C(C)C)=O)CCC2)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCCN)=O)CCCCN)=O)=O)C(C)C)=O)CCC1)=O)CCCCN)=O)=O)CC8=CNC9=CC=CC=C89)=O)CCCNC(N)=N)=O)CC%10=CC=CC=C%10)=O)CC%11=CNC=N%11)=O)CCC(O)=O)=O)CCSC)=O)CO)=O)CC%12=CC=C(O)C=C%12

Molecular Formula

C207H308N56O58S

Molecular Weight

4541.14

Precautions

H302+H312+H332, H351

References & Citations

[1]Lisak RP, et al. Melanocortin receptor agonist ACTH 1-39 protects rat forebrain neurons from apoptotic, excitotoxic and inflammation-related damage. Exp Neurol. 2015 Nov;273:161-7.|[2]Lisak RP, et al. The melanocortin ACTH 1-39 promotes protection of oligodendrocytes by astroglia. J Neurol Sci. 2016 Mar 15;362:21-6.