Aegeline (Standard)

Aegeline (Standard) is the analytical standard of Aegeline. This product is intended for research and analytical applications. Aegeline, a main alkaloid, mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast. Aegeline restores growth of yeast cells suppressed by either αsyn or Bax. Antioxidant activity[1].

Product Specifications

CAS Number

[456-12-2]

UNSPSC

12352005

Target

Fungal; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/aegeline-standard.html

Smiles

O=C(NCC(O)C1=CC=C(OC)C=C1)/C=C/C2=CC=CC=C2

Molecular Formula

C18H19NO3

Molecular Weight

297.35

References & Citations

[1]Derf A, et al. a natural product from the plant Aegle marmelos, mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast [published correction appears in Bioorg Med Chem Lett. 2019 Aug 15;29 (16) :2437-2438]. Bioorg Med Chem Lett. 2019;29 (3) :454‐460.|[2]Nugroho AE, et al. Effects of aegeline, a main alkaloid of Aegle Marmelos Correa leaves, on the histamine release from mast cells. Pak J Pharm Sci. 2011;24 (3) :359‐367.