Phosphofructokinase, Bacillus stearothermophilus

Phosphofructokinase from Bacillus stearothermophilus is a key enzyme in sugar metabolism that catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate during glycolysis. The enzyme's ability to bind fructose-6-phosphate can be inhibited by phosphoenolpyruvate (PEP), thereby regulating the rate of glycolysis. Phosphofructokinase from Bacillus stearothermophilus can be used for the measurement of fructose-6-phosphate levels[1][2].

Product Specifications

CAS Number

[9001-80-3]

UNSPSC

12352204

Target

Endogenous Metabolite

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/phosphofructokinase-bacillus-stearothermophilus.html

Smiles

[Phosphofructokinase,Bacillusstearothermophilus]

References & Citations

[1]Kimmel JL, et al. Reevaluation of the accepted allosteric mechanism of phosphofructokinase from Bacillus stearothermophilus. Proc Natl Acad Sci U S A. 2000 Apr 11;97 (8) :3844-9.|[2]Byrnes M, et al. Kinetic characteristics of phosphofructokinase from Bacillus stearothermophilus: MgATP nonallosterically inhibits the enzyme[J]. Biochemistry, 1994, 33 (11) : 3424-3431.