AA 497 (free base)
AA 497 free base is an adrenergic beta-2 agonist. AA 497 free base is a bronchodilator[1][2].
Product Specifications
CAS Number
59605-49-1
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/aa-497-free-base.html
Smiles
O[C@@H]1[C@H](CCC2=C1C=CC(O)=C2CO)NC(C)C
Molecular Formula
C14H21NO3
Molecular Weight
251.32
References & Citations
[1]Inatomi N, et al. Pharmacological studies of trans-6-hydroxy-5-hydroxymethyl-2-isopropylamino-1,2,3,4, -tetrahydro-1-naphthalenol hydrochloride (AA-497), a new potent bronchodilator. Arzneimittelforschung. 1980;30 (2) :276-85.|[2]Kimura I, et al. Difference between adrenergic beta 1- and beta 2-blocking effects on isoproterenol-induced Ca spike suppression in guinea-pig taenia coli. Jpn J Pharmacol. 1983 Dec;33 (6) :1271-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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