N-Ethylmaleimide-d5
N-Ethylmaleimide-d5 is the deuterium labeled N-Ethylmaleimide. N-Ethylmaleimide (NEM), a reagent that alkylates free sulfhydryl groups, is a cysteine protease inhibitor[1]. N-ethylmaleimide specific inhibits phosphate transport in mitochondria[2]. N-Ethylmaleimide is also a deubiquitinating enzyme inhibitor[3].
Product Specifications
CAS Number
360768-37-2
Product Name Alternative
NEM-d5
UNSPSC
12352005
Hazard Statement
H300, H311, H314, H317
Target
Cathepsin; Deubiquitinase
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Field of Research
Others
Purity
99.90
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : 12.5mg/mL (ultrasonic) |H2O : 50mg/mL (ultrasonic)
Smiles
O=C(C=C1)N(C([2H])([2H])C([2H])([2H])[2H])C1=O
Molecular Formula
C6H2D5NO2
Molecular Weight
130.16
Precautions
H300, H311, H314, H317
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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