JH-LPH-107
JH-LPH-107 is a LpxH inhibitor. JH-LPH-107 exhibits a low rate of spontaneous resistance and a high safety window in vitro.[1].
Product Specifications
CAS Number
[3053068-92-8]
UNSPSC
12352211
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jh-lph-107.html
Smiles
O=C(NC1=CC=C(S(=O)(N2CCN(C3=NC(Cl)=CC(C(F)(F)F)=C3)CC2)=O)C=C1)C4=CC=CC=C4N(C)S(=O)(C)=O
Molecular Formula
C25H25ClF3N5O5S2
Molecular Weight
632.07
References & Citations
[1]Ennis AF, et al. Design and Evaluation of Pyridinyl Sulfonyl Piperazine LpxH Inhibitors with Potent Antibiotic Activity Against Enterobacterales. JACS Au. 2024 Nov 11;4 (11) :4383-4393.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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