Isolicoflavonol

Isolicoflavonol potently inhibits hCES2A (Human carboxylesterase 2) -mediated fluorescein diacetate hydrolysis in a reversible and mixed inhibition manner, with Ki values less than 1.0 μM[1].

Product Specifications

CAS Number

[94805-83-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Carboxylesterase (CES)

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/isolicoflavonol.html

Purity

99.70

Smiles

O=C1C(O)=C(C2=CC(C/C=C(C)\C)=C(O)C=C2)OC3=C1C(O)=CC(O)=C3

Molecular Formula

C20H18O6

Molecular Weight

354.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Song YQ, et al. Discovery of hCES2A inhibitors from Glycyrrhiza inflata via combination of docking-based virtual screening and fluorescence-based inhibition assays. Food Funct. 2021;12 (1) :162-176.