Isolicoflavonol
Isolicoflavonol potently inhibits hCES2A (Human carboxylesterase 2) -mediated fluorescein diacetate hydrolysis in a reversible and mixed inhibition manner, with Ki values less than 1.0 μM[1].
Product Specifications
CAS Number
[94805-83-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Carboxylesterase (CES)
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/isolicoflavonol.html
Purity
99.70
Smiles
O=C1C(O)=C(C2=CC(C/C=C(C)\C)=C(O)C=C2)OC3=C1C(O)=CC(O)=C3
Molecular Formula
C20H18O6
Molecular Weight
354.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Song YQ, et al. Discovery of hCES2A inhibitors from Glycyrrhiza inflata via combination of docking-based virtual screening and fluorescence-based inhibition assays. Food Funct. 2021;12 (1) :162-176.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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