PROTAC ACC degrader-1
PROTAC ACC degrader-1 (Compound 9b) is a Acetyl-CoA Carboxylase degrader. PROTAC ACC degrader-1 exhibits superior potency against Aphis craccivora (IC50 = 107.8 μg/mL). (Structure Note: Pink, Target protein ligand ; Blue, E3 ligand (HY-10984) ; Black, linker (HY-W007559).
Product Specifications
UNSPSC
12352005
Target
Acetyl-CoA Carboxylase; PROTACs
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; PROTAC
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/protac-acc-degrader-1.html
Smiles
CC1=C(C2=C(OCCCCCC(NC3=C(C(N(C4C(NC(CC4)=O)=O)C5=O)=O)C5=CC=C3)=O)C6(CCC(OC)CC6)NC2=O)C=C(C)C=C1
Molecular Formula
C37H42N4O8
Molecular Weight
670.75
References & Citations
[1]Xu Q, et al. Acetyl-CoA Carboxylase Proteolysis-Targeting Chimeras: Conceptual Design and Application as Insecticides. J Agric Food Chem. 2024 Aug 28;72 (34) :18809-18815.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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