PE Anti-Human TCR Vα24-Jα18 Antibody[6B11]
Selected Variant
AN00568D-01
Size: 20 Tests
Product Specifications
Background
Encoded by the TCR Vα24-Jα18 germline configuration, Vα24-JαQ is expressed on a subset of NKT cells, namely invariant NKT (iNKT) . Vα24-JαQ TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production. iNKT cells have been implicated in immune regulation, tumor surveillance, and host response to pathogens. While iNKT cells occur at low frequency in the blood, assorted chemokines contribute to their tissue homing potential.
Abbreviation
TCR Vα24-Jα18
Gene ID
28659
Host
Mouse
Reactivity
Human
Target
TCR Vα24-Jα18; TCR Vα24-JαQ; invariant NKT cell; iNKT
Clonality
Monoclonal
Clone
6B11
Conjugation
PE
Applications
FCM
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG1
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