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PE Anti-Human TCR Vα24-Jα18 Antibody[6B11]

Product Specifications

Background

Encoded by the TCR Vα24-Jα18 germline configuration, Vα24-JαQ is expressed on a subset of NKT cells, namely invariant NKT (iNKT) . Vα24-JαQ TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production. iNKT cells have been implicated in immune regulation, tumor surveillance, and host response to pathogens. While iNKT cells occur at low frequency in the blood, assorted chemokines contribute to their tissue homing potential.

Abbreviation

TCR Vα24-Jα18

Gene ID

28659

Host

Mouse

Reactivity

Human

Target

TCR Vα24-Jα18; TCR Vα24-JαQ; invariant NKT cell; iNKT

Clonality

Monoclonal

Clone

6B11

Conjugation

PE

Applications

FCM

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Product Datasheet

https://789.bio/ea/vqmehc

Product MSDS

https://789.bio/eb/OZPRlS

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG1

Available Sizes

Curated Selection

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