Dihydrocytochalasin B
Dihydrocytochalasin B (H2CB) is a Cytokinesis inhibitor and changes the morphology of the cells, similar to that of cytochalasin B; does not inhibit glucose transport[1]. Dihydrocytochalasin B (H2CB) disrupts the actin structure and inhibits the ability of growth factors to stimulate DNA synthesis, reversibly blocks initiation of DNA synthesis[2]. Dihydrocytochalasin B (H2CB) inhibits active calcium transport and causes a Ca2+increase in the mucosal scrapings[3].
Product Specifications
CAS Number
[39156-67-7]
UNSPSC
12352005
Hazard Statement
H300+H310+H330, H351
Target
Arp2/3 Complex
Type
Natural Products
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dihydrocytochalasin-b.html
Purity
99.0
Solubility
DMF : 30 mg/mL (ultrasonic; warming) |DMSO : ≥ 20 mg/mL
Smiles
O=C1[C@]2(O3)[C@]([C@@H](C([C@@H](O)[C@]2([H])/C=C/C[C@@H](CCC[C@@H](O)CCC3=O)C)=C)C)([H])[C@H](CC4=CC=CC=C4)N1
Molecular Formula
C29H39NO5
Molecular Weight
481.62
Precautions
H300+H310+H330, H351
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
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