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CAIX/CAXII-IN-3

CAIX/CAXII-IN-3 (compound 11) is an inhibitor of CAIX/CAXII, with an IC50 value of less than 65 nM. CAIX/CAXII-IN-3 inhibits the proliferation of human melanoma cells[1].

Product Specifications

UNSPSC

12352211

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/caix-caxii-in-3.html

Smiles

OB1C2=CC(NC(NCC3=CC=CC=C3)=S)=CC=C2CCO1

Molecular Formula

C16H17BN2O2S

Molecular Weight

312.19

References & Citations

[1]Giovannuzzi S, et al. Benzoxaborinine, New Chemotype for Carbonic Anhydrase Inhibition: Ex Novo Synthesis, Crystallography, In Silico Studies, and Anti-Melanoma Cell Line Activity. J Med Chem. 2024 Oct 8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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