CAIX/CAXII-IN-3
CAIX/CAXII-IN-3 (compound 11) is an inhibitor of CAIX/CAXII, with an IC50 value of less than 65 nM. CAIX/CAXII-IN-3 inhibits the proliferation of human melanoma cells[1].
Product Specifications
UNSPSC
12352211
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/caix-caxii-in-3.html
Smiles
OB1C2=CC(NC(NCC3=CC=CC=C3)=S)=CC=C2CCO1
Molecular Formula
C16H17BN2O2S
Molecular Weight
312.19
References & Citations
[1]Giovannuzzi S, et al. Benzoxaborinine, New Chemotype for Carbonic Anhydrase Inhibition: Ex Novo Synthesis, Crystallography, In Silico Studies, and Anti-Melanoma Cell Line Activity. J Med Chem. 2024 Oct 8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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