Bacterial Type I Signal Peptidase FRET Substrate

<strong>Bacterial Type I Signal Peptidase FRET Substrate</strong>_x000D_ <strong>Catalog number:</strong> B2011397_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1494.6 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> SPase1 substrate_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Szałaj N, Benediktsdottir A, Rusin D, Karlén A, Mowbray SL, Więckowska A. Bacterial type I signal peptidase inhibitors - Optimized hits from nature Eur J Med Chem. 2022 Aug 5;238:114490._x000D_ 2: Craney A, Romesberg FE. The inhibition of type I bacterial signal peptidase: Biological consequences and therapeutic potential Bioorg Med Chem Lett. 2015 Nov 1;25(21):4761-4766._x000D_ 3: Tuteja R. Type I signal peptidase: an overview Arch Biochem Biophys. 2005 Sep 15;441(2):107-11._x000D_ 4: Smitha Rao CV, Anné J. Bacterial type I signal peptidases as antibiotic targets Future Microbiol. 2011 Nov;6(11):1279-96._x000D_ 5: Benediktsdottir A, Lu L, Cao S, Zamaratski E, Karlén A, Mowbray SL, Hughes D, Sandström A. Antibacterial sulfonimidamide-based oligopeptides as type I signal peptidase inhibitors: Synthesis and biological evaluation Eur J Med Chem. 2021 Nov 15;224:113699._x000D_ 6: Paetzel M. Structure and mechanism of Escherichia coli type I signal peptidase Biochim Biophys Acta. 2014 Aug;1843(8):1497-508._x000D_ 7: Siegel SD, Wu C, Ton-That H. A Type I Signal Peptidase Is Required for Pilus Assembly in the Gram-Positive, Biofilm-Forming Bacterium Actinomyces oris J Bacteriol. 2016 Jul 13;198(15):2064-73._x000D_ 8: Hazenbos WL, Skippington E, Tan MW. Staphylococcus aureus type I signal peptidase: essential or not essential, that's the question Microb Cell. 2017 Mar 17;4(4):108-111._x000D_ 9: Paetzel M. Bacterial Signal Peptidases Subcell Biochem. 2019;92:187-219._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/21075926">10: Powers ME, Smith PA, Roberts TC, Fowler BJ, King CC, Trauger SA, Siuzdak G, Romesberg FE. Type I signal peptidase and protein secretion in Staphylococcus epidermidis J Bacteriol. 2011 Jan;193(2):340-8. </a>_x000D_ _x000D_ <strong>Products Related to Bacterial Type I Signal Peptidase FRET Substrate can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>