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MET-IN-1

MET-IN-1 (Compound 13) is an orally active MET inhibitor. MET-IN-1 has antitumor activity[1].

Product Specifications

UNSPSC

12352005

Target

C-Met/HGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/met-in-1.html

Smiles

O=C(NC(C=C1F)=C(C=C1N(C2=NC=CN3C2=CC=N3)[C@H]4C[C@@H](C4)C5=NN(C=C5)C)F)C6=CC=NN(C6=O)C7=NC=C(C=C7)F

Molecular Formula

C30H23F3N10O2

Molecular Weight

612.56

References & Citations

[1]Bumpers QA, et al. Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial Efficacy. J Med Chem. 2024 Aug 1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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