MET-IN-1
MET-IN-1 (Compound 13) is an orally active MET inhibitor. MET-IN-1 has antitumor activity[1].
Product Specifications
UNSPSC
12352005
Target
C-Met/HGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/met-in-1.html
Smiles
O=C(NC(C=C1F)=C(C=C1N(C2=NC=CN3C2=CC=N3)[C@H]4C[C@@H](C4)C5=NN(C=C5)C)F)C6=CC=NN(C6=O)C7=NC=C(C=C7)F
Molecular Formula
C30H23F3N10O2
Molecular Weight
612.56
References & Citations
[1]Bumpers QA, et al. Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial Efficacy. J Med Chem. 2024 Aug 1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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