Phospho-KSR1 (Ser392) Antibody SureLight Conjugate

<strong>Phospho-KSR1 (Ser392) Antibody SureLight Conjugate </strong>_x000D_ <strong>Catalog number:</strong> B2018574_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 102.16 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8℃_x000D_ <strong>Keywords:</strong> Kinase suppressor of Ras 1_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Rao C, Frodyma DE, Southekal S, Svoboda RA, Black AR, Guda C, Mizutani T, Clevers H, Johnson KR, Fisher KW, Lewis RE. KSR1- and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition Elife. 2021 May 10;10:e66608._x000D_ 2: Roskoski R Jr. ERK1/2 MAP kinases: structure, function, and regulation Pharmacol Res. 2012 Aug;66(2):105-43._x000D_ 3: Parvathaneni S, Li Z, Sacks DB. Calmodulin influences MAPK signaling by binding KSR1 J Biol Chem. 2021 Jan-Jun;296:100577._x000D_ 4: Ingersoll MA, Lutze RD, Kelmann RG, Kresock DF, Marsh JD, Quevedo RV, Zuo J, Teitz T. KSR1 knockout mouse model demonstrates MAPK pathway's key role in cisplatin- and noise-induced hearing loss bioRxiv [Preprint]. 2023 Nov 13:2023.11.08.566316._x000D_ 5: Ingersoll MA, Lutze RD, Kelmann RG, Kresock DF, Marsh JD, Quevedo RV, Zuo J, Teitz T. KSR1 Knockout Mouse Model Demonstrates MAPK Pathway's Key Role in Cisplatin- and Noise-induced Hearing Loss J Neurosci. 2024 May 1;44(18):e2174232024._x000D_ 6: Zhang H, Koo CY, Stebbing J, Giamas G. The dual function of KSR1: a pseudokinase and beyond Biochem Soc Trans. 2013 Aug;41(4):1078-82._x000D_ 7: Lee J, Seol MY, Jeong S, Kwon HJ, Lee CR, Ku CR, Kang SW, Jeong JJ, Shin DY, Nam KH, Lee EJ, Chung WY, Jo YS. KSR1 is coordinately regulated with Notch signaling and oxidative phosphorylation in thyroid cancer J Mol Endocrinol. 2015 Apr;54(2):115-24._x000D_ 8: Kolesnick R, Xing HR. Inflammatory bowel disease reveals the kinase activity of KSR1 J Clin Invest. 2004 Nov;114(9):1233-7._x000D_ 9: Daley BR, Vieira HM, Rao C, Hughes JM, Beckley ZM, Huisman DH, Chatterjee D, Sealover NE, Cox K, Askew JW, Svoboda RA, Fisher KW, Lewis RE, Kortum RL. SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status Proc Natl Acad Sci U S A. 2023 Nov 21;120(47):e2313137120._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/35508574">10: Maloney RC, Zhang M, Liu Y, Jang H, Nussinov R. The mechanism of activation of MEK1 by B-Raf and KSR1 Cell Mol Life Sci. 2022 May 4;79(5):281. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-KSR1 (Ser392) Antibody SureLight Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Conjugates/"> Conjugates</a>