Mequitazine (Standard)
Mequitazine (Standard) is the analytical standard of Mequitazine. This product is intended for research and analytical applications. Mequitazine is a potent, and long-acting histamine H1 antagonist.
Product Specifications
CAS Number
29216-28-2
Product Name Alternative
LM-209 (Standard)
UNSPSC
12352005
Hazard Statement
H301
Target
Histamine Receptor; Reference Standards
Type
Reference Standards
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/mequitazine-standard.html
Purity
99.92
Smiles
C12=CC=CC=C1N(CC3CN4CCC3CC4)C5=C(C=CC=C5)S2
Molecular Formula
C20H22N2S
Molecular Weight
322.47
Precautions
H301
References & Citations
[1]Gonnot V, et al. Expedient synthesis of mequitazine an antihistaminic drug by palladium catalyzed allylic alkylation of sodium phenothiazinate. Chem Pharm Bull (Tokyo) . 2009 Nov;57 (11) :1300-2.|[2]El-Nakeeb MA, et a. In vitro antibacterial activity of some antihistaminics belonging to different groups against multi-drug resistant clinical isolates. Braz J Microbiol. 2011 Jul;42 (3) :980-91.|[3]Martinez-Mir I, et al. Antihistaminic and anticholinergic activities of mequitazine in comparison with clemizole. J Pharm Pharmacol. 1988 Sep;40 (9) :655-6.|[4]Satake N, et al. Possible mechanisms of vasoinhibitory effects of mequitazine, an antiallergic agent, on the contractions of isolated rat aorta induced by K+, phenylephrine, 5-hydroxytryptamine, and Ca2+. J Cardiovasc Pharmacol. 1994 Apr;23 (4) :669-73.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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