CEP-11981
CEP-11981 (ESK981; BOL 303213X) is an orally active tyrosine kinase inhibitor (TKI), which can target TIE2, VEGFR1-3 and FGFR1, and has potential anti-tumor and anti-angiogenic effects[1].
Product Specifications
CAS Number
[856691-93-5]
Product Name Alternative
ESK981; BOL 303213X
UNSPSC
12352005
Target
FGFR; VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cep-11981.html
Purity
99.18
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC(C)CN(C1=C2C3=C(C(NC3)=O)C4=C1CCC5=NN(C)C=C54)C(C2=C6)=CC=C6NC7=NC=CC=N7
Molecular Formula
C28H27N7O
Molecular Weight
477.56
References & Citations
[1]Weiguo Jian, et al. The angiopoietin-TIE2 pathway is a potential therapeutic target in urothelial carcinoma. Anticancer Res. 2014 Jul;34 (7) :3377-82.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7141560 Inquire
Rabbit anti-Escherichia coli O139:H28 (strain E24377A/ETEC) ORN Polyclonal Antibody
Ask
View Details RHG-40-600 1 mL
DiagNano™ Anti-Human IgG conjugated Gold Nanorods, diameter 40 nm, absorption max 600 nm
Ask
View Details