Ac-WEHD-AFC
Ac-WEHD-AFC is a fluorogenic caspase-1 substrate. Ac-WEHD-AFC can measure caspase-1 fluorogenic activity and can be used for the research of tumor and inflammation[1].
Product Specifications
CAS Number
210344-99-3
UNSPSC
12352209
Target
Caspase; Fluorescent Dye
Type
Peptides
Related Pathways
Apoptosis; Others
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ac-wehd-afc.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C(C(C(O1)=C2)=CC=C2NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC3=CNC4=CC=CC=C34)=O)=O)CC5=CN=CN5)=O)=O)=CC1=O)F
Molecular Formula
C38H37F3N8O11
Molecular Weight
838.74
References & Citations
[1]Katherine Labbé, et al. Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome. Immunity
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Caspase 1
Frequently Asked Questions
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