3-Methoxy-9H-Carbazole

3-Methoxy-9H-Carbazole induces caspase-3 activities and the cellular generation of eactive oxygen species. 3-Methoxy-9H-Carbazole inhibits cancer cell proliferation and induces apoptosis[1].

Product Specifications

CAS Number

[18992-85-3]

UNSPSC

12352005

Hazard Statement

H302

Target

Apoptosis; Caspase; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/3-methoxy-9h-carbazole.html

Purity

99.64

Solubility

10 mM in DMSO

Smiles

COC1=CC2=C(NC3=C2C=CC=C3)C=C1

Molecular Formula

C13H11NO

Molecular Weight

197.24

Precautions

H302

References & Citations

[1]Alanazi J, et al. 3-Methoxy Carbazole Impedes the Growth of Human Breast Cancer Cells by Suppressing NF-κB Signaling Pathway. Pharmaceuticals (Basel) . 2022 Nov 14;15 (11) :1410.