Sp-8-PIP cAMP
Sp-8-PIP cAMP sodium is a non-corresponding isomer of 8-Piperidino-cAMP. 8-Piperidino-cAMP binds with high affinity to site A of the regulatory subunit of cAMP-dependent protein kinase type I (AI) . Sp-8-PIP cAMP sodium can be used as an antagonist of cAMP-induced activation[1].
Product Specifications
CAS Number
[156816-35-2]
UNSPSC
12352005
Target
PKA
Type
Reference compound
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sp-8-pip-camp.html
Smiles
O[C@@H]1[C@H](O2)[C@@H](CO[P@@]2(S)=O)O[C@H]1N(C(N3CCCCC3)=N4)C5=C4C(N)=NC=N5
Molecular Formula
C15H21N6O5PS
Molecular Weight
428.40
References & Citations
[1]Ogreid D, et al. (Rp) - and (Sp) -8-piperidino-adenosine 3',5'- (cyclic) thiophosphates discriminate completely between site A and B of the regulatory subunits of cAMP-dependent protein kinase type I and II. Eur J Biochem. 1994 May 1;221 (3) :1089-94.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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