Sp-8-PIP cAMP

Sp-8-PIP cAMP sodium is a non-corresponding isomer of 8-Piperidino-cAMP. 8-Piperidino-cAMP binds with high affinity to site A of the regulatory subunit of cAMP-dependent protein kinase type I (AI) . Sp-8-PIP cAMP sodium can be used as an antagonist of cAMP-induced activation[1].

Product Specifications

CAS Number

[156816-35-2]

UNSPSC

12352005

Target

PKA

Type

Reference compound

Related Pathways

Stem Cell/Wnt; TGF-beta/Smad

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sp-8-pip-camp.html

Smiles

O[C@@H]1[C@H](O2)[C@@H](CO[P@@]2(S)=O)O[C@H]1N(C(N3CCCCC3)=N4)C5=C4C(N)=NC=N5

Molecular Formula

C15H21N6O5PS

Molecular Weight

428.40

References & Citations

[1]Ogreid D, et al. (Rp) - and (Sp) -8-piperidino-adenosine 3',5'- (cyclic) thiophosphates discriminate completely between site A and B of the regulatory subunits of cAMP-dependent protein kinase type I and II. Eur J Biochem. 1994 May 1;221 (3) :1089-94.