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4-Chlorosalicylic acid

4-Chlorosalicylic acid is a pharmaceutical intermediate. Inhibits monophenolase and diphenolase activity with IC50s of 1.89 mM and 1.10 mM. Potent antimicrobial activity. Against E. coli with the MIC of 250 μg/mL and with the MBC of 500 μg/mL.

Product Specifications

CAS Number

[5106-98-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/4-Chlorosalicylic_acid.html

Concentration

10mM

Purity

99.95

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

C1=CC(=CC(=C1C(O)=O)O)Cl

Molecular Formula

C7H5ClO3

Molecular Weight

172.57

Precautions

H302, H315, H319, H335

References & Citations

[1]Han P, et al. Inhibitory effects of 4-chlorosalicylic acid on mushroom tyrosinase and its antimicrobial activities. 107 (2), 797-803, 2008

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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