4-Chlorosalicylic acid
4-Chlorosalicylic acid is a pharmaceutical intermediate. Inhibits monophenolase and diphenolase activity with IC50s of 1.89 mM and 1.10 mM. Potent antimicrobial activity. Against E. coli with the MIC of 250 μg/mL and with the MBC of 500 μg/mL.
Product Specifications
CAS Number
[5106-98-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/4-Chlorosalicylic_acid.html
Concentration
10mM
Purity
99.95
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
C1=CC(=CC(=C1C(O)=O)O)Cl
Molecular Formula
C7H5ClO3
Molecular Weight
172.57
Precautions
H302, H315, H319, H335
References & Citations
[1]Han P, et al. Inhibitory effects of 4-chlorosalicylic acid on mushroom tyrosinase and its antimicrobial activities. 107 (2), 797-803, 2008
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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