β-Amyloid peptide (16-20)

β-Amyloid peptide (16-20) is a amino acid sequences (KLVFF) of Amyloid-β (Abeta) . β-Amyloid peptide (16-20) is an effective inhibitor of Abeta fibril formation, with RG-/-GR-NH2 residues added at N- and C-terminal ends to aid solubility) [1].

Product Specifications

CAS Number

[153247-40-6]

Product Name Alternative

KLVFF

UNSPSC

12352209

Target

Amyloid-β

Type

Peptides

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/β-amyloid-peptide-16-20.html

Purity

99.95

Solubility

H2O : 33.33 mg/mL (ultrasonic)

Smiles

NCCCC[C@H](N)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O)CC2=CC=CC=C2)=O)=O)=O

Molecular Formula

C35H52N6O6

Molecular Weight

652.82

References & Citations

[1]Austen BM, et al. Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's beta-amyloid peptide. Biochemistry. 2008 Feb 19;47 (7) :1984-92.