Sulfamethoxazole 1000 µg/mL in methanol

Sulfamethoxazole (Ro 4-2130) 1000 μg/mL in methanol is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole 1000 μg/mL in methanol inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole 1000 μg/mL in methanol can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis[1][2][3].

Product Specifications

CAS Number

[723-46-6]

Product Name Alternative

Ro 4-2130 1000 µg/mL in methanol

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial

Type

Biochemical Assay Reagents

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sulfamethoxazole-1000-g-ml-in-methanol.html

Purity

90.0

Smiles

O=S(NC1=NOC(C)=C1)(C2=CC=C(C=C2)N)=O

Molecular Formula

C10H11N3O3S

Molecular Weight

253.28

Precautions

H302, H315, H319, H335

References & Citations

[1]Zambuzzi-Carvalho et al. Transcriptional profile of the human pathogenic fungus Paracoccidioides lutzii in response to sulfamethoxazole. Med Mycol. 2015;53 (5) :477-492. |[2]Choonara BF, et al. A menthol-based solid dispersion technique for enhanced solubility and dissolution of sulfamethoxazole from an oral tablet matrix. AAPS PharmSciTech. 2015 Aug;16 (4) :771-86.|[3]Ogata H, et al. Dose Dependent Effect of Sulfamethoxazole on Inhibiting KATP Channel of Mouse Pancreatic β Cell. Dose Response. 2023 Sep 28;21 (3) :15593258231203611.