FEN1-IN-SC13

FEN1-IN-SC13 is a potent DNA fragmentation endonuclease 1 (FEN1) inhibitor with antitumor activity. FEN1-IN-SC13 interferes with DNA replication and repair in vitro and in cells[1].

Product Specifications

CAS Number

[2098776-03-3]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Endonuclease

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fen1-in-sc13.html

Purity

98.42

Solubility

DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(NC1=CC=CC(CN(C(C=CS2)=C2C(N3CCC)=O)C3=O)=C1)CC4=CC=CC=C4

Molecular Formula

C24H23N3O3S

Molecular Weight

433.52

Precautions

H315, H319

References & Citations

[1]Application of small-molecular inhibitor SC13 targeting to FEN1 and derivative of small-molecular inhibitor SC13 in preparing tumor treatment medicine. CN106692155A.