FEN1-IN-SC13
FEN1-IN-SC13 is a potent DNA fragmentation endonuclease 1 (FEN1) inhibitor with antitumor activity. FEN1-IN-SC13 interferes with DNA replication and repair in vitro and in cells[1].
Product Specifications
CAS Number
[2098776-03-3]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Endonuclease
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fen1-in-sc13.html
Purity
98.42
Solubility
DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=CC=CC(CN(C(C=CS2)=C2C(N3CCC)=O)C3=O)=C1)CC4=CC=CC=C4
Molecular Formula
C24H23N3O3S
Molecular Weight
433.52
Precautions
H315, H319
References & Citations
[1]Application of small-molecular inhibitor SC13 targeting to FEN1 and derivative of small-molecular inhibitor SC13 in preparing tumor treatment medicine. CN106692155A.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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