CPCCOEt

CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of metabotropic glutamate receptor 1b (mGluR1b) [1][2].

Product Specifications

CAS Number

[179067-99-3]

UNSPSC

12352005

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cpccoet.html

Purity

98.13

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C12C(C2)/C(C3=CC=CC=C3O1)=N\O)OCC

Molecular Formula

C13H13NO4

Molecular Weight

247.25

References & Citations

[1]Litschig S, et al. CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding. Mol Pharmacol. 1999 Mar;55 (3) :453-61. |[2]Hermans E, et al. Reversible and non-competitive antagonist profile of CPCCOEt at the human type 1alpha metabotropic glutamate receptor. Neuropharmacology. 1998 Dec;37 (12) :1645-7.