Trichomide A
Product Specifications
CAS Number
[1569195-36-3]
UNSPSC Description
Trichomide A is a potent activator of SHP2. Trichomide A is a natural cyclodepsipeptide. Trichomide A displays immunosuppressive activity against activated T lymphocyte–mediated immune responses in Con A-activated T cells. Trichomide A have the potential for the research of immune-related skin diseases[1].
Target Antigen
Phosphatase; SHP2
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease;Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/trichomide-a.html
Solubility
10 mM in DMSO
Smiles
CC[C@@H]([C@H]1C(N(C)[C@@H]([C@H](CC)C)C(N(C)[C@@H](C)C(NCCC(O[C@H](C[C@H](CO)C)C(N2CC[C@H](C)[C@H]2C(N1)=O)=O)=O)=O)=O)=O)C
Molecular Weight
637.81
References & Citations
[1]Song Y, et al. Strategies Targeting Protein Tyrosine Phosphatase SHP2 for Cancer Therapy. J Med Chem. 2022;65(4):3066-3079.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
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