1-Docosanol

1-Docosanol (Behenyl alcohol) is a saturated fatty alcohol with reported inhibitory activity against lipid-enveloped viruses, including herpes simplex virus (HSV) [1][2].

Product Specifications

CAS Number

[661-19-8]

Product Name Alternative

Behenyl alcohol

UNSPSC

12352211

Hazard Statement

H319, H410

Target

HSV

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/1-Docosanol.html

Purity

99.84

Solubility

DMSO : < 1 mg/mL (ultrasonic) |Ethanol : 10 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL

Smiles

CCCCCCCCCCCCCCCCCCCCCCO

Molecular Formula

C22H46O

Molecular Weight

326.60

Precautions

H319, H410

References & Citations

[1]Katz DH, et al. Antiviral activity of 1-docosanol, an inhibitor of lipid-enveloped viruses including herpes simplex. Proc Natl Acad Sci U S A. 1991 Dec 1;88 (23) :10825-9.|[2]Sacks SL, et al. Clinical efficacy of topical docosanol 10% cream for herpes simplex labialis: A multicenter, randomized, placebo-controlled trial. J Am Acad Dermatol. 2001 Aug;45 (2) :222-30.|[3]Iglesias G, et al. The toxicity of behenyl alcohol. I. Genotoxicity and subchronic toxicity in rats and dogs. Regul Toxicol Pharmacol. 2002 Aug;36 (1) :69-79.