FAP Ligand 2
FAP Ligand 2, a FAPI-46 derivative, is a specific fibroblast activation protein (FAP) -targeted tracer. FAP Ligand 2 exhibits good tumor uptake and acts as a promising molecular tracer for FAP tumor imaging[1].
Product Specifications
UNSPSC
12171500
Target
FAP
Type
Dye Reagents
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/99mtc-tc-6-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=NC2=CC=C(C=C21)N(CCCN3CCN(CC3)C([C@@H]4CCCN4C(C5=CN=C(C=C5)N/N=C/C6=C(C=CC=C6)S(=O)(O[Na])=O)=O)=O)C)NCC(N7CC(F)(C[C@]7(C#N)[H])F)=O
Molecular Formula
C43H46F2N11NaO7S
Molecular Weight
921.95
References & Citations
[1]Qing Ruan, et al. Synthesis and Preclinical Evaluation of Novel 99mTc-Labeled FAPI-46 Derivatives with Significant Tumor Uptake and Improved Tumor-to-Nontarget Ratios. J Med Chem. 2024 Feb 22;67 (4) :3190-3202.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
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