FAP Ligand 2

FAP Ligand 2, a FAPI-46 derivative, is a specific fibroblast activation protein (FAP) -targeted tracer. FAP Ligand 2 exhibits good tumor uptake and acts as a promising molecular tracer for FAP tumor imaging[1].

Product Specifications

UNSPSC

12171500

Target

FAP

Type

Dye Reagents

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/99mtc-tc-6-1.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=NC2=CC=C(C=C21)N(CCCN3CCN(CC3)C([C@@H]4CCCN4C(C5=CN=C(C=C5)N/N=C/C6=C(C=CC=C6)S(=O)(O[Na])=O)=O)=O)C)NCC(N7CC(F)(C[C@]7(C#N)[H])F)=O

Molecular Formula

C43H46F2N11NaO7S

Molecular Weight

921.95

References & Citations

[1]Qing Ruan, et al. Synthesis and Preclinical Evaluation of Novel 99mTc-Labeled FAPI-46 Derivatives with Significant Tumor Uptake and Improved Tumor-to-Nontarget Ratios. J Med Chem. 2024 Feb 22;67 (4) :3190-3202.