PAOPA
Product Specifications
UNSPSC Description
PAOPA, an analog of L-proline-l-leucine-glycine amide (PLG) peptide, is an allosteric modulator of Dopamine D2 Receptor. PAOPA can effectively reduce behavioral abnormalities in rodent models of schizophrenia. PAOPA increases the high affinity dopamine D2 receptor and promotes its binding to agonists[1].
Target Antigen
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/paopa.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H]1CCCN1)N[C@H]2C(N(CC2)CC(N)=O)=O
Molecular Weight
254.29
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-103423/PAOPA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-103423/
Clinical Information
No Development Reported
CAS Number
114200-31-6
Available Sizes
Curated Selection
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