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Allopregnanolone

Positive allosteric modulator of GABAA receptors

Product Specifications

Background

Allopprenanolone is a natural metabolite of progesterone that is devoid of any progestational activity. It acts and functions as a potent ligand of GABA type A receptor complexes in the CNS. It is a neuroactive steroid. Has recently been approved as a drug for postpartum depression by the FDA.

CAS Number

516-54-1

Product Name Alternative

(3α,5α) -3-Hydroxy-pregnan-20-one; (3α,5α) -tetrahydroprogesterone; 3-OH-DHP

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cell Signaling | Neuroscience

Purity

>98% (HPLC) ; NMR (Conforms)

Weight

0.005

Format

White to off-white powder

Solubility

May be dissolved in DMSO (32 mg/ml); or Ethanol (32 mg/ml)

Molecular Formula

C21H34O2

Molecular Weight

318.5

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

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