Phytosphingosine
Kinase Activator
Product Specifications
Background
Phytosphingosine is a naturally occurring component found in yeast, plants and animals. In yeast, it is involved in mediating the heat stress response. Phytosphingosine has been found to be pro-apoptotic in certain cancer cell lines. It is thought to activate the p38 MAPK pathway, followed by release of cytochrome c and activation of caspase 3, ultimately leading to programed cell death.
CAS Number
554-62-1
Product Name Alternative
(2S,3R,4R) -Octadecane-1,2,3,4-tetraol
UNSPSC
41116105
Type
Activator
Source
Isolated from Saccharomyces cerevisiae
Field of Research
Cancer | Oxidative Stress
Purity
>98% (TLC) ; NMR (Conforms)
Weight
0.005
Format
White powder
Solubility
Soluble to 2 mg/ml in ethanol
Molecular Formula
C18H39NO3
Molecular Weight
317.5
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Fischer C., et al. (2013) Skin Pharmacol Physiol. 26(1): 36-44.
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